Download Atlas of Medical Renal Pathology by Stephen M. Bonsib (auth.) PDF
By Stephen M. Bonsib (auth.)
The kidney is an organ with advanced organogenesis at risk of various misadventures in improvement and is uncovered to a various array of insults of hematogenous and decrease urinary tract starting place. This Atlas of clinical Renal Pathology offers an summary of the advance, macroscopic and microscopic beneficial properties of the traditional kidney. this can be via a complete survey of developmental and cystic kidney illnesses, vascular illnesses and tubulointerstitial ailments. An emphasis is put on gross diagnostic findings with distinctive histological correlates. furthermore, the histological, immunofluorescent, immunohistochemical and ultrastructural gains of the main glomerular illnesses and renal transplantation pathology are provided. This compendium of non-neoplastic kidney ailments illustrates the overwhelming majority ailments you will definitely come across in surgical and post-mortem pathology.
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In contrast to ADPKD, however, the kidney in ACKD is grossly smaller because it is affected by ESKD prior to cystic alteration. Histologically, there would be advanced nephrosclerosis and tubulointerstitial scarring Fig. 60 ADPKD. This is another example of a cyst with papillary hyperplasia. 62 ACKD. This end-stage kidney shows advanced ACKD and appears grossly similar to that seen in ADPKD. However, this kidney is only 12 cm in length, much smaller than a similarly affected kidney in ADPKD. In addition, the patient was known to have been on dialysis for many years and did not have cysts at the initiation of dialysis Fig.
24 Ask-Upmark segmental hypoplasia. This is a hypoplastic focus from the specimen shown in Fig. 23. It demonstrates the abrupt transition from normal cortex to the hypoplastic focus. The hypoplastic focus contains dilated veins, hypertrophied arteries, and several small tubules, but no glomeruli. No tubular atrophy or glomerulosclerosis is present Fig. 25 Segmental hypoplasia. This hypoplastic segment from the kidney of a 33-year-old woman shows how narrow the hypoplastic foci may be. Notice the normal cortex on both sides of the lesion and the characteristic abrupt transition.
56 ADPKD. This case of advanced ADPKD shows multiple large cysts. 3 Acquired Cystic Kidney Disease ACKD is defined by the presence of three or more cysts, bilaterally, in the native kidneys of patients with ESKD whose original disease was not the result of a cystic kidney disease. Development of ACKD is common among dialysis patients, and its incidence increases over time. By 10 years on dialysis, most patients will be affected. A major concern with ACKD is development of renal cell carcinoma (RCC), which will occur in approximately 10 % of affected patients.