Download Encyclopedia of cancer by Joseph R Bertino PDF
By Joseph R Bertino
Because the booklet of the 1st version of the Encyclopedia of Cancer, an grand volume of latest info has been disseminated within the box of melanoma study. This moment variation strives to seize the advances happening within the etiology, prevention, and therapy of melanoma, from uncomplicated technology to medical program. by way of offering concise expositions on a large variety of themes, the Encyclopedia is a wonderful source for these looking info past their particular components of craftsmanship. Written by means of a distinct panel of authors, entries hide numerous points of melanoma equivalent to oncology, immunology, epidemiology, gene treatment, oncogenes/tumor suppressor genes, and pharmacology. This awesome reference is key for a person inquisitive about the research or therapy of melanoma.
An on-line model of the Encyclopedia of Cancer is obtainable on ScienceDirect. stopover at http://info.sciencedirect.com/reference_works/ for touch and subscription details. entry strategies can be found whether you are not an present ScienceDirect shopper!
Key Features
* Covers all features of melanoma, segueing from uncomplicated technology to medical topics
* comprises an extra quantity to include all of the new advances within the etiology, prevention, and remedy of melanoma made because the first edition
* handy association employs commonplace access structure for speedy and simple reference
* huge cross-referencing offers reader with broader diversity of knowledge
* Contributions solicited from one of the best names in various fields
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Extra resources for Encyclopedia of cancer
Sample text
J. (1992). Cell-mediated cleavage of pseudomonas exotoxin between Arg279 and Gly280 generates the enzymatically active fragment which translocates to the cytosol. J. Biol. Chem. 267(35), 25396–25401. Pai, L. , Gallo, M. , FitzGerald, D. , and Pastan, I. (1991). Anti-tumor activity of a transforming growth factor ␣-Pseudomonas exotoxin fusion protein (TGF␣-PE40). Cancer Res. 51, 2808–2812. Pai, L. , and Pastan, I. (1993). Immunotoxin therapy for cancer. JAMA 269(1), 78–81. , and FitzGerald, D. J.
Hematol. 6, 135–144. Cancer Vaccines: Peptideand Protein-Based Vaccines Paul F. Robbins National Institutes of Health, Bethesda, Maryland major histocompatibility complex (MHC) Locus encoding polymorphic genes utilized by the immune systems for antigen presentation and for self/nonself recognition. melanocyte Skin cell responsible for the production of the pigment melanin. transfection Introduction of DNA into a cell using physical manipulation. I. Major Histocompatibility Complex Class I- and Class II-Restricted T-Cell Recognition II.
Anti-idiotypic MAbs offer a similar advantage in immunizing against nonprotein tumor antigens. B-cell responses to nonprotein antigens (T-cell independent) are generally low-titer, transient IgM responses. Anti-idiotypic MAbs that mimic nonprotein antigens represent a xenogeneic protein mimic that can be more immunogenic than the original nonprotein antigen. Presumably, one of the ways this could occur is that the anti-idiotypic MAb can provide TH cell epitopes, which the B cell can present to TH cells through its MHC class II molecules.