Download Histology and Cell Biology: An Introduction to Pathology, 4e by Abraham L Kierszenbaum M.D. Ph.D., Laura Tres M.D. Ph.D. PDF
By Abraham L Kierszenbaum M.D. Ph.D., Laura Tres M.D. Ph.D.
Totally integrating histology, cellphone biology, and pathology, the 4th variation of the award-winning Histology and mobilephone Biology: An advent to Pathology provides key strategies in an comprehensible, easy-to-digest demeanour. Authors Abraham L. Kierszenbaum, MD, PhD and Laura L. Tres MD, PhD hyperlink uncomplicated technological know-how to scientific software all through, targeting what you want to understand on your coursework now - and the way to apply �Read more...
summary: absolutely integrating histology, phone biology, and pathology, the 4th variation of the award-winning Histology and cellphone Biology: An creation to Pathology offers key recommendations in an comprehensible, easy-to-digest demeanour. Authors Abraham L. Kierszenbaum, MD, PhD and Laura L. Tres MD, PhD hyperlink easy technology to medical program all through, concentrating on what you must be aware of to your coursework now - and the way to use that details in a medical environment . Full-color illustrations on each web page, in addition to specific, student-friendly gains on-line, assist you speedy clutch the complexities of pathologic abnormalities
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Extra resources for Histology and Cell Biology: An Introduction to Pathology, 4e
Example text
During axonemal transport, particles are mobilized by kinesin and cytoplasmic dynein along the microtubule doublets of the axoneme. Defective axonemal transport results in the abnorCytoskeleton 1. EPITHELIUM 27 Figure 1-32. Classes of myosin molecules and how they work Myosin II Proteolytic cleavage of myosin II at specific sites Subfragment S1 F-actin Actin-binding and ATPase domains. The myosin II head provides the driving force for movement. ATP drives the movement of myosin heads along actin filaments.
Cofilin (also known as actin depolymerizing factor) triggers depolymerization of ADP-bound actin at the pointed end. Similar to profilin and thymosin, cofilin forms a dimeric complex with G-actin. 4. Gelsolin has a dual role: it is a capping protein and prevents the loss and addition of actin monomers, and it is a severing protein. In the presence of Ca2+, gelsolin fragments actin filaments and remains bound to the barbed end, forming a cap that prevents further filament growth. Type IV collagen Nidogen (entactin) Macula adherens (spot desmosome) Desmosomes are symmetrical structures consisting of: (1) plaques containing desmoplakins, plakoglobin and plakophilins (2) linking cadherins (mainly desmocollins and desmogleins) and (3) keratin filaments attached to the plaques.
5. Cadherins and the afadin-nectin complex are present in tight junctions and zonula adherens. Actin microfilaments are associated with these two junctions but there is a difference: catenins are present in zonula adherens but not in tight junctions. Cytoskeleton Box 1-D | Periodic acid–Schiff (PAS) reaction • PAS is a widely used histochemical technique to show 1,2-glycol or 1,2-aminoalcohol groups, such as those present in glycogen, mucus, and glycoproteins. • Periodic acid, an oxidant, converts these groups to aldehydes.