Download Molecular Pathology and Diagnostics of Cancer by Jesse Kresak, Yuan (Frank) Shan M.D. (auth.), Domenico PDF
By Jesse Kresak, Yuan (Frank) Shan M.D. (auth.), Domenico Coppola (eds.)
Molecular pathology relies at the emergence of latest recommendations that drastically improve the diagnostic accuracy whilst dealing with with not easy differential diagnoses. furthermore, new molecular options are coming into the scientific enviornment for his or her price in predicting remedy reaction and tumor analysis. This e-book offers a advisor for the working towards pathologist and for either pathology citizens and fellows in the course of the day-by-day sign-out of tough situations. The e-book is geared up through anatomical platforms and gives a close description of molecular exams which could assist in the prognosis. in addition, an outline of the present molecular exams required to spot sufferers for remedy is out there. the applying of molecular pathology strategies to the medical perform has already proven its usefulness and the variety of such assessments is turning out to be exponentially as extra molecular ambitions are chanced on. Molecular Pathology and Diagnostics of melanoma will provide training and coaching pathologists an up-to date source to lead the right kind administration of pathology circumstances requiring molecular testing.
Read Online or Download Molecular Pathology and Diagnostics of Cancer PDF
Similar pathology books
Forensic Psychology For Dummies
Taking into account a occupation that indulges your CSI fantasies? are looking to comprehend the psychology of crime? even if learning it for the 1st time or an spectator, Forensic Psychology For Dummies provides the entire necessities for figuring out this fascinating box, complemented with interesting case examples from worldwide.
Cardiac tumors have been as soon as a nosographic entity of scarce scientific curiosity a result of rarity and of the intrinsic diagnostic and healing impossibilities, and have been thought of a deadly morbid entity. It has now develop into a topical topic because of advances in medical imaging (echo, magnetic resonance, computed tomography) in addition to innovation in applied sciences of in-vivo analysis.
The Pathology of the Endocrine Pancreas in Diabetes
Diabetes mellitus represents essentially the most widespread and severe medical syn dromes in modern drugs. because the finish of the 19th century, the endocrine pancreas has been implicated within the pathogenesis of this sickness. numerous pathologists of the 20th century detected quite a few lesions and mor phologic adjustments within the pancreatic islets of diabetic sufferers, however the patho physiologic foundation in their findings remained lengthy imprecise.
- The Pathology of Devices
- Molecular Cytopathology
- Color Atlas of Pathophysiology
- High-Yield Histopathology
- Pathology of Pediatric Gastrointestinal and Liver Disease
- Digital Pathology: Historical Perspectives, Current Concepts & Future Applications
Extra info for Molecular Pathology and Diagnostics of Cancer
Example text
In: Rosai J, Sobin LH (eds) Atlas of tumor pathology. 3rd series, fascicle 6. Armed Forces Institute of Pathology, Washington, DC, pp 3–63 4. Clayman GL, Gonzalez HE, El-Naggar A, Vassilopoulou-Sellin R (2004) Parathyroid carcinoma: evaluation and interdisciplinary management. Cancer 100:900–905 5. Enewold L, Zhu K, Ron E, Marrogi AJ, Stojadinovic A, Peoples GE, Devesa SS (2009) Rising thyroid cancer incidence in the United States by demographic and tumor characteristics, 1980-2005. Cancer Epidemiol Biomarkers Prev 18:784–791 6.
3 Reverse Transcriptase-PCR in the Diagnosis of MTC Thyroid tumors are often diagnosed by cytologic examination of FNAs. In some cases a diagnosis is not possible due to inadequate FNA sampling, poor fixation, or a lack of epithelial cells. To facilitate diagnosis in such cases Takano et al. [155] developed a new molecular technique termed aspiration biopsy-reverse transcriptase-PCR. In this technique, cells left over in the FNA needle are used for reverse transcriptase-PCR of genes specifically expressed in one TC type.
BRAF V660E mutations were found in 38 % of PTCs in an Italian population, with a tendency for the mutation frequency to increase with increasing patient age. 5 DNA Sequencing DNA sequencing has often been employed in BRAF mutation analyses [58, 61]. Although considered the gold standard in molecular testing, especially Sanger sequencing, direct sequencing has several disadvantages: (1) it can be relatively expensive, especially for longer sequences; (2) other techniques such as ASA-PCR and STAT have higher sensitivity; and (3) it can give false results when applied to formalin-fixed tissue [62, 63].