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By Virginia J. Baldwin

Pathology of a number of Pregnancy collates case fabric from over 500 autopsies (including embryos) and 1200 placentas from twins, triplets, and better multiples with chosen literature on human a number of copy. It emphasizes very important new ideas of pathophysiology and interpretation of below excellent results of a number of perception in line with over 30 years adventure within the box. elements of perinatal pathology special to twins and better multiples are emphasised, with sensible feedback for the provider pathologist, together with goods of capability medico-legal value. arguable issues, comparable to the worth of experiences of concordance for illnesses or malformations, and the importance of inter-twin anastomoses, are addressed and recommendations made for additional research. a detailed operating dating among pathologists and medical colleagues is inspired through dialogue of clinico-pathological correlations. And, the newest discussions on mechanisms of twinning and genetic as opposed to environmental affects at the improvement of twins are presented.

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Pathology of the Placenta. New York: Churchill Livingstone; 1984:165-182. 114. James W. A hypothesis on the declining dizygotic twinning rates in developed countries. In: Nance WE, ed. Twin Research: Biology and Epidemiology. Prog ClinBiol Res. 1978;24B:81-88. 115. Lazar P, Hemon D, Berger C. Twinning rate and reproductive failure. In: Nance WE, ed. Twin Research: Biology and Epidemiology. Prog Clin BioI Res. 1978;24B:125-132. 116. Twins at Jerusalem (Editorial). Lancet. 1980; 2:244-245. 117. ~mith SM, Penrose LS.

111. Layde PM, Erickson JD, Falek A, McCarthy BJ. Congenital malformations in twins. Am } Hum Genet. 1980;32:69-78. 28 112. Hrubec Z, Robinette CD. The study of human twins in medical research. N EngLJ Med. 1984;310:435441. 113. Shanklin DR, Perrin EVDK. Multiple gestation. In: Perrin EVDK, ed. Pathology of the Placenta. New York: Churchill Livingstone; 1984:165-182. 114. James W. A hypothesis on the declining dizygotic twinning rates in developed countries. In: Nance WE, ed. Twin Research: Biology and Epidemiology.

An apparent single sac that is actually due to complete separation of the amnion is more common than a truly single monoamniotic sac. 7. At this stage of the stepwise examination of a singledisk twin placenta, the cord and free membranes of the fIrst twin have been described and sections taken. The cord and membranes of the second twin are examined next, followed by the septum. 8. In this dichorionic diamniotic fused twin placenta, the outer membranes of sac A (cord with suture tie) are tom. Through the gap can be seen the rupture site in the separating membranes or septum, through which twin B was born.

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