Download Pathology of Vascular Skin Lesions: Clinicopathologic by Omar P. Sangüeza MD, Luis Requena MD (auth.) PDF
By Omar P. Sangüeza MD, Luis Requena MD (auth.)
Cutaneous vascular proliferations are awfully universal, and with the new id of latest illnesses, their analysis, category, and therapy may be advanced. In Pathology of Vascular pores and skin Lesions: Clinicopathologic Correlations, Omar P. Sangüeza, md, and Luis Requena, md, evaluation intimately all of the vascular proliferations concerning the outside and subcutaneous tissue, together with lately defined ailment entities. beautifully illustrated with either medical and histopathologic photos, the publication strikes from a proposed new approach of type and nomenclature for vascular neoplasms, to a whole dialogue of benign and malignant proliferations, together with hamartomas, benign neoplasms, and a number of other newly said similar ailments. The authors supply an in-depth description of the medical and morphologic features of every entity and aspect their clinicopathologic correlation, differential analysis, analysis, and remedy. extra chapters define the conventional embryology, histology, and anatomy of pores and skin vasculature, in addition to using unique ideas for the research of vascular proliferations.
Comprehensive and sensible, Pathology of Vascular pores and skin Lesions: Clinicopathologic Correlations presents dermatologists, pathologists, and pores and skin researchers with a whole, authoritative advisor to the prognosis and remedy of vascular proliferations of the surface, all generously illustrated with a wide-ranging array of medical instances and histopathologic specimens.
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Additional info for Pathology of Vascular Skin Lesions: Clinicopathologic Correlations
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42. Sigg C, Pelloni F. Oligo symptomatic form of Klippel-Trenaunay-Weber syndrome associated with giant nevus spilus. Arch Dermatol1989;125:1284-5. 43. Guiglia MC, Prendiville JS. Multiple granular cell tumors associated with giant speckled lentiginous nevus and nevus flammeus in a child. JAm Acad Dermatol1991;24:359-63. 44. Libow LF. Phakomatosis pigmentovascularis type IIIb. J Am Acad Dermatol1993; 29:305-7. 45. Smoller BR, Rosen S. Port wine stains: a disease of altered neural modulation of blood vessels?
There are two hypotheses that attempt to explain this dilation. One suggests either a defect in the vascular wall or abnormalities of the supporting structure of the dermis surrounding the dilated vessels. Immunofluorescence studies of the different components of the vessel wall, including type IV collagen, fibronectin, and factor VIII, disclosed no abnormalities in lesions of port wine stains (72). Comparative studies of normal blood vessels and vessels of port wine stains utilizing immunohistochemical analysis with four monoclonal antibodies specific for endothelial cells (PAL-E, anti-factor VIII-related antigen, anti-intercellular adhesion molecule-I, and anti-endothelial leukocyte adhesion molecule-I) demonstrated no substantial differences, either in the intensity of staining or the distribution pattern of these antibodies (73).
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