Download The Hippocampus from Cells to Systems: Structure, by Deborah E. Hannula, Melissa C. Duff PDF
By Deborah E. Hannula, Melissa C. Duff
The hippocampus has lengthy been thought of a severe substrate within the neurobiology, neuropsychology, and cognitive neuroscience of reminiscence. over the last few many years, a few ground-breaking theoretical and methodological advances have greatly more advantageous our realizing of the constitution and serve as of the hippocampus and revolutionized the neuroscientific research of reminiscence. slicing throughout disciplines and techniques, those advances provide novel insights into the molecular and mobile constitution and body structure of the hippocampus, the position of hippocampus within the formation, (re)consolidation, enhancement, and retrieval of reminiscence throughout time and improvement, and allow investigators to deal with questions on how the hippocampus interacts, functionally and anatomically, with different neural structures in carrier of reminiscence. additionally, fresh investigations additionally recommend that the mechanistic houses and useful processing positive factors of the hippocampus allow broader contributions to cognition, past reminiscence, to the domain names of awareness, decision-making, language, social cognition, and numerous different capacities which are severe for versatile cognition and behaviour. those advances have profound implications for the neurobiology and cognitive neuroscience of hippocampus established cognition and for the varied psychiatric and neurological illnesses and issues for which hippocampal pathology is a trademark comparable to Alzheimer’s sickness and schizophrenia.
The target of this booklet is to compile in one resource an built-in evaluation of those advances delivering state-of-the-art remedy at the constitution and serve as of the hippocampus. individuals will research the hippocampus from a number of degrees (from cells to structures) utilizing a variety of tools (from neurobiological ways in non-human animals to neuroimaging and neuropsychological paintings in humans).
Read or Download The Hippocampus from Cells to Systems: Structure, Connectivity, and Functional Contributions to Memory and Flexible Cognition PDF
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Extra info for The Hippocampus from Cells to Systems: Structure, Connectivity, and Functional Contributions to Memory and Flexible Cognition
Example text
The EC reciprocates the projection to the RSC. The termination pattern of EC efferent projections to the RSC are typically concentrated in layer I of area 29; lighter projections are directed to area 30, and layer III of the posterior cingulate cortex. The caudal part of the EC (subfield ECL) provides more widespread RSC projections (Morris et al. 1999a; Kobayashi and Amaral 2003; Aggleton et al. 2012). In addition, retrograde tracing experiments demonstrate that other fields of the HF such as the S, PrS and PaS send projections to the RSC (Vogt and Pandya 1987; Morris et al.
In addition, retrograde tracing experiments demonstrate that other fields of the HF such as the S, PrS and PaS send projections to the RSC (Vogt and Pandya 1987; Morris et al. 1999b; Kobayashi and Amaral 2003; Aggleton et al. 2012). Projections from the S and PrS terminate principally in layers I and III of area 29. The Nonhuman Primate Hippocampus: Neuroanatomy and Patterns of Cortical. . 29 While the uncal part of the S projects primarily to the ventral RSC, mid and caudal levels of the S have denser projections to both the caudal and dorsal RSC.
On the ventral surface there is a transitional zone, area 30v, which separates RSC from prestriate visual cortex (Kobayashi and Amaral 2003). The RSC receives afferents from the HF, the PHR, other cingulate cortical areas, LPFC, and parietal cortex (Goldman-Rakic et al. 1984; Kobayashi and Amaral 2003). Therefore, the RSC has potential to exert a substantial influence on HF function. The cytoarchitectonic organization of the macaque monkey RSC and caudal portion of the cingulate cortices has been previously described (Kobayashi and Amaral 2000).