Download A Short History of the Drug Receptor Concept (Science, by Andreas-Holger Maehle, Cay-Rüdiger Prüll, Robert Francis PDF
By Andreas-Holger Maehle, Cay-Rüdiger Prüll, Robert Francis Halliwell
The receptor thought was once the most influential rules in 20th-century drugs since it may well account for the hugely particular results of gear at the physique. This e-book is the 1st to supply an old dialogue of its foundation, improvement, gradual attractiveness into pharmacology and next influence on smooth medication. It additionally considers the social context that inspired the drug receptor's development., creating a invaluable contribution to the background and figuring out of contemporary drugs.
Read or Download A Short History of the Drug Receptor Concept (Science, Technology and Medicine in Modern History) PDF
Similar history_1 books
His Christmas Pleasure (Avon, Historical Romance)
Paperback. Pub Date :2010-11-30 Pages: 384 Language: English writer: HarperCollins US Sylvias kinfolk Soul nutrients Cookbook starts off as Sylvia recollects her adolescence. while she lived with either her mom and her grandmother - the cities merely midwives the complete. group of Hemingway. South Carolina. shared duties.
The Black Abolitionist Papers: Vol. V: The United States, 1859-1865
This five-volume documentary collection—culled from a world archival seek that became up over 14,000 letters, speeches, pamphlets, essays, and newspaper editorials—reveals how black abolitionists represented the middle of the antislavery circulate. whereas the 1st volumes think of black abolitionists within the British Isles and Canada (the domestic of a few 60,000 black american citizens at the eve of the Civil War), the remainder volumes research the actions and reviews of black abolitionists within the usa from 1830 till the top of the Civil struggle.
The New Cambridge History of India, Volume 3, Part 3: The Economy of Modern India, 1860-1970
This is often the 1st entire and interpretative account of the heritage of financial progress and alter in colonial and post-colonial India. Dr. Tomlinson attracts jointly and expands at the expert literature facing imperialism, improvement and underdevelopment, the historic approaches of switch in agriculture, exchange and manufacture, and the family members between company, the economic system and the country.
- Haynes Honda XL XR600R Owners Workshop Manual: 1983-2000
- Butchers Hill (Tess Monaghan Mysteries - Book 03 - 1998)
- Oeuvres mathematiques, extrait des oeuvres completes t.9, edition de Assezat (1875-1877)
- Liore et Olivier LeO 45 Series
- Classical Literature and Its Times: Profiles of Notable Literary Works and the Historical Events That Influenced Them (World Literature and Its Times, Volume 8)
- Su-15Tm Flagon
Additional resources for A Short History of the Drug Receptor Concept (Science, Technology and Medicine in Modern History)
Example text
Moreover, the antagonism between the two poisons could be demonstrated locally, by way of direct application, in different parts of the heart. 6 In this way Langley’s work on jaborandi provided supporting evidence for Foster’s view that the heartbeat had a muscular, not a nervous origin. Yet, this was not its only significance. At the very start of his career, Langley had hit upon a problem that would recur again and again in the course of his experimental work and that ultimately led him to his theory of receptive substances: do drugs act directly on the effector cells (in this case, the heart cells) or do they primarily affect the endings of nerves terminating in the organ tissues?
The young Langley was especially attracted by Foster’s classes in elementary biology, embryology and physiology. Foster, who had been appointed as praelector of physiology at Trinity College in 1870, held to the principle of providing his students from early on with the opportunity to acquire first-hand knowledge through their own experimental work in his physiological laboratory, in those days a single room that was also used for lectures. Even before Langley graduated with a BA in 1875, Foster had involved him in his research programme.
Ehrlich repeatedly asked them to test his substances. Even if the clinicians were prepared, in principal, to undertake the experiments, Ehrlich had to press them forcefully to do the test and to report the results. The system did not work well and from June 1899 at the latest Ehrlich showed signs of frustration. 140 In the end, dye testing appears to have been a futile attempt to restore the old Charité conditions, where laboratory work and animal experimentation could be linked with clinical expertise.