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By T. Frieden

The second one variation of this sensible, authoritative reference e-book offers a rational foundation for the analysis and administration of tuberculosis. Written by means of a few specialists within the box, it continues to be devoted to Kurt Toman's unique question-and-answer structure, with subject material grouped below the 3 headings Case Detection, remedy, and tracking. it's a testomony to the iconic nature of the 1st variation that quite a bit fabric has been retained unchanged. while, the recent variation has had not just to deal with the massive resurgence of tuberculosis, the emergence of multi-drug-resistant bacilli, and the certain wishes of HIV-infected people with tuberculosis, but in addition to surround major medical advances. those adjustments within the profile of the disorder and in methods to administration have unavoidably brought on many new questions and solutions and given a unique complexion to others. Toman's Tuberculosis continues to be crucial interpreting for all who have to research extra approximately each element of tuberculosis - case-finding administration and potent keep an eye on options. It presents necessary aid to someone within the entrance line of the conflict in contrast affliction, from application managers to policy-makers and from scientific team of workers to volunteer medical examiners. Now additionally to be had in Spanish during the Pan American healthiness association TUBERCULOSIS: Detecci?n de casos tratamiento y vigilancia. Preguntas y respuestas

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Extra resources for Toman's Tuberculosis: Case Detection, Treatment and Monitoring

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More recently, using DNA fingerprinting 1 2 Based on the chapter by K. Toman in the first edition. Mycobacteriology Unit, Institute of Tropical Medicine, Antwerp, Belgium. 35 TOMAN’S TUBERCULOSIS techniques, similar percentages of cross-contamination have been found repeatedly in routine laboratories in countries where the prevalence of tuberculosis is low (2, 3). In countries with a high prevalence of tuberculosis, the specificity of smear microscopy may thus be superior to that of culture. This may be true even for the diagnosis of tuberculosis (4), since AFB demonstrated in direct sputum smears would then almost invariably represent M.

Slides should never be used more than once for the detection of AFB. False-negative results False-negative results (1–6) may be due to deficiencies in the preparation, staining, or examination of the smear. Proper collection of the specimen and subsequent selection of sputum particles are essential to the preparation of a smear and should receive special attention. Poor quality of the sputum sample is the most common reason for a negative sputum smear in a patient with smear-positive tuberculosis.

5. Mitchison DA. Proceedings of the 6th International Congress of Tropical Medicine and Malaria, Lisbon, 5–13 September 1958. Vol 4. Porto, Imprensa Portuguesa, 1959. 6. Mitchison DA. Examination of sputum by smears and culture in case finding. Bulletin of the International Union Against Tuberculosis, 1968, 41:139–147. 7. Mitchison DA. Bacteriological aspects of mycobacterial infections. British Medical Journal, 1972, 1:424–425. 8. Mitchison DA. Bacteriology of tuberculosis. Tropical Doctor, 1974, 4:147–153.

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